表观产品-小分子抑制剂-smyd5 Antibody

Datasheet

Description

Retinoic acid (RA) represents the oxidized form of vitamin A and, via interactions with retinoic acid receptors (RARs), plays a crucial role in development, cellular growth and differentiation. The gene encoding RAI15 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr?m syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Uniprot

Q6GMV2

Alternative Names

Protein NN8 4AG; Protein NN8-4AG; retinoic acid induced 15; retinoic acid responsive; retinoic acid responsive gene 1; Retinoic acid-induced protein 15; SET and MYND domain-containing protein 5; AW536703; NN8-4AG; RAI15; RRG1; SMYD5; ZMYND23;

Reactivity

Human, Mouse, Rat

Source

Mouse

Application

Mol Weight

47KD

Storage Condition

Store at -20 °C. Stable for 12 months from date of receipt.

Application

WB 1:500-1:2000, IHC 1:50-1:200; IP 1:50-1:100

M30070

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