Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4) AR DHTR NR3C4

Human, Mouse, Rat

WB,IP,IF

WB 1:500-1:2000, IHC 1:50-1:200; IP 1:50-1:100

99KD

AR DHTR NR3C4

P10275

https://www.uniprot.org/uniprotkb/p10275

Mouse

Monoclonal

Mouse IgG

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.