表观产品-小分子抑制剂-ABH7 Antibody

Datasheet

Description

May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate. Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism (By similarity).

Uniprot

Q9BT30

Alternative Names

ABH7; ALKB7_HUMAN; ALKBH7; Alkylated DNA repair protein alkB homolog 7; MGC10974; Probable alpha-ketoglutarate-dependent dioxygenase ABH7; SPATA11; Spermatogenesis cell proliferation-related protein; Spermatogenesis-associated protein 11; UNQ6002; UNQ6002/PRO34564;

Reactivity

Human, Mouse, Rat

Source

Mouse

Application

Mol Weight

24KD

Storage Condition

Store at -20 °C. Stable for 12 months from date of receipt.

Application

WB 1:500-1:2000, IHC 1:50-1:200; IP 1:50-1:100

M30163

货号 规格 价格(¥)
订购咨询 orders@ab-mart.com
技术支持 service3@ab-mart.com

订货热线 4006-123-828

经销商名录:点击查看


banner-500.jpg

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162127138

技术支持:13162477137

总机:021-34695901


wx.png

      微信客服

邮箱:market@ab-mart.com

总机:021-34695901

热线:13166434152 

订购专线:4006-123-828

wx.png

微信客服

沪ICP备17056956号-2    艾比玛特医药科技(上海)有限公司