表观产品-小分子抑制剂-MLL4 Antibody

Datasheet

Description

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.





Uniprot

Q9UMN6





Alternative Names

Histone-lysine N-methyltransferase 2B; histone-lysine N-methyltransferase 2B-like; histone-lysine N-methyltransferase MLL4; KMT2D; lysine (K)-specific methyltransferase 2B; Lysine N-methyltransferase 2B; mixed lineage leukemia 2; mixed lineage leukemia gene homolog 2; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; Myeloid/lymphoid or mixed-lineage leukemia protein 4; Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog; Trithorax homolog 2; trithorax homologue 2; WBP-7; WW domain binding protein 7; WW domain-binding protein 7; 2610014H22Rik; CXXC10; HRX2; KIAA0304; KMT2B; mKIAA0304; MLL1B; MLL2; MLL4; TRX2; WBP-7; WBP7;





Specificity

MLL4 Antibody detects endogenous levels of total MLL4.





Reactivity

Human, Mouse, Rat





Application

Source

Mouse



Mol.Wt.

300kDa





Storage Condition

Store at -20 °C. Stable for 12 months from date of receipt.





Application

WB 1:1000-1:2000;IHC/IF 1:50-1:500


image.png

Western blot analysis of extracts from HUVEC whole cell, using MLL4 Antibody.





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Storage Condition

Store at -20°C long term.

M007816

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