LysineacetylationisanimportantreversiblemodificationcontrollingproteinactivityInvariousspecies,acetylationoflysineresiduesisanimportantformofproteinposttranslationalmodification(PTM)thataffectsthousandsofproteinssuchasHistones,transcriptfactors,IFNreceptors,aswellasP53,tubulin,Hsp9othatrangingfromnuclearregulatorstocytosolicproteins,mitochondrialenzymes,andplasmamembraneassociatedreceptors(1)Theregulationofproteinacetylationisinvolvedincontrolofcellcycle,metabolism,cellsignaling,nucleartransportandevenotherPTMprocess(1,2,3)[1]:Xiang-jiaoYetal.(2008)MolecularCell31,449-461[2]:ChoudharyCetal.(2014)NatureReviewsMolecularCellBiology15,536-550[3]:Choudhary,Cetal.(2009)Science325.834-40

All

WB

Immunoprecipitationgt;10ougantibodywith5oulCnbr-sepharose4B/ProteinASepharosebeads WesternBlot1:200-1:1000

Mouse

Monoclonal

Mouse IgG

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20°C long term.

TargetAcetylated-lvsineHostReactivityAllspeIsotypeMouselag

AB_2936273