SRPSOX

Measure by its ability to chemoattract BaF3 cells transfected with mouse CXCR6
The ED50 for this effect is <3 ng/mL.

CXCL16 belongs to the CXC chemokine family and conducts signaling through the CXCR6 receptor. CXCL16 may act as an attractant of lymphocyte subsets during inflammation process and may facilitate certain immune responses. Among six cysteine residues of the chemokine domain, there are four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene encodes a 273 amino acid polypeptide, which contains a 29 amino acid cytoplasmic domain and a 20 amino acids transmembrane sequence.

Q8BSU2

66102

NQGSVAGSCSCDRTISSGTQIPQGTLDHIRKYLKAFHRCPFFIRFQLQSKSVCGGSQDQWVRELVDCFERKECGTGHGKSFHHQKHLP with polyhistidine tag at the N-terminus.

His-tag?at?the?N-terminus

Mouse

Mouse

Escherichia coli

E. coli

>98% as determined by SDS-PAGE. Ni-NTA chromatography

<0.1 EU per 1 μg of the protein by the LAL method.

10.74 kDa

The protein was lyophilized from a solution containing 1X PBS, pH 7.4.

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Blue Ice

Lyophilized protein should be stored at -20°C for 1 year.
Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1%
BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Cytokines

Cell culture, Elisa