信号通路Signaling-VIME(337) Mouse mAb

Datasheet

Background

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract

Source

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human VIME

Alternative Names

VIME

Uniport

P08670

Alternative Names

VIM

Application

Recommanded Dilutions

Western blotting 1:1000-1:5000
Immunoprecipitation 10 tests
FACS 1:100-1:200

Predicted Mol Weight

53.6kDa

Storage

Store at -20°C, stable for one year from the date of shipment.

Reactivity

Human

Isotype

Mouse IgG

M25003

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