The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) NDUFS1

Human

WB,IP,FACS

Western blotting 1:1000-1:5000 Immunoprecipitation 10 tests FACS 1:100-1:200

79.4kDa

NDUFS1

P28331

https://www.uniprot.org/uniprotkb/p28331

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human NDUFS1

Mouse

Monoclonal

Mouse IgG

Transmembrane

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20°C, stable for one year from the date of shipment.