Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.

Catabolin; H1; IL 1; IL 1 beta; IL-1 beta; IL1 BETA; IL1B; IL1B_HUMAN; IL1F2; Interleukin 1 beta; Interleukin-1 beta; OAF; OTTHUMP00000162031; Preinterleukin 1 beta; Pro interleukin 1 beta;

P01584

31kD; 31kDa(Calculated).

Mouse

IL1B antibody detects endogenous levels of total IL1B.

Human

WB,IHC,IF/ICC,ELISA
 Recommended dilution
WB 1:500-1:2000  IHC  1:50-1:500  IF/ICC  1:50-1:500  ELISA  1：2000

Store at -20 °C. Stable for 12 months from date of receipt.

AB_2920646