补体Complement-Factor B Antibody

Datasheet

Description

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Uniport

P00751

Alternative Names

C3/C5 convertase; Complement factor B; Glycine-rich beta glycoprotein; PBF2; Properdin factor B;

Reactivity

Human, Mouse, Rat

Source

Mouse monoclonal

Application

Mol Weight

86kDa

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

Application

WB 1:500-1:2000

M057757

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