Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin) MBL2 COLEC1 MBL

Human, Mouse, Rat

WB

WB 1:500-1:2000

26kDa

MBL2 COLEC1 MBL

P11226

https://www.uniprot.org/uniprotkb/p11226

Mouse

Monoclonal

Mouse IgG

Acute phase #Complement pathway #Complement activation lectin pathway #Innate immunity #defense response to bacterium #proteolysis,

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at -20 °C. Stable for 12 months from date of receipt.