Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation (PubMed:16338136, PubMed:16421191, PubMed:16466390).Required for oocyte maturation, embryonic development, germline proliferation and initiation of meiosis during spermatogenesis (PubMed:11702779, PubMed:12397109, PubMed:27104746).Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (PubMed:16421191).
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3;
O18209
77kDa
Mouse monoclonal
Caenorhabditis elegans
WB 1:500-1:2000
Store at -20 °C. Stable for 12 months from date of receipt.
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
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