信号通路Signaling-Caspase-7 Antibody

Datasheet

Background

Caspase-7, apoptosis-related cysteine peptidase, also known as CASP7, is a human protein encoded by the CASP7 gene. Caspase-7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. The precursor of this caspase is cleaved by caspase 3, caspase 10, and caspase 9. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

Source

This Abmart monoclonal antibody is produced by immunizing animals with a polypeptide (Abmart SEAL mAb technology) corresponding to Caspase-7 protein.

Protein Name

Caspase-7

UniProt

P55210

Alternative Names

CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3, ICE-LAP3, MCH3

Application

Recommend Antibody Dilutions

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Molecular Weight

34kDa

Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Reactivity

Human

Isotype

Rabbit IgG

T40049

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