Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Caveolin-1 CAV1 CAV

Human

WB,IHC,ICC/IF,FCM

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

25kDa

CAV1 CAV

q03135

https://www.uniprot.org/uniprotkb/q03135

A synthesized peptide derived from human Caveolin-1

Rabbit

Monoclonal

Rabbit IgG

Caveolin-1 Antibody detects endogenous levels of total Caveolin-1

Transmembrane

Angiogenesis #Calcium transport #Differentiation

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.