ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

ER; ESR; ESR1; Era; ESRA; NR3A1;

p03372

60kDa

Rabbit IgG

A synthesized peptide derived from human ER alpha

ER alpha Antibody detects endogenous levels of total ER alpha

Human Mouse Rat Dog

Affinity-chromatography

WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 ChIP 1:50~1:100 FC 1:30 

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.