经典一抗-Vinculin Antibody

Datasheet

Background

Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration.

Alternative Name

Vinculin (Metavinculin) (MV) VCL

Reactivity

Human Mouse Rat

Predicted Reactivity

Application

WB,ICC/IF,IP

Application Image

Recommanded Dilution

WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50

Mol Weight

125kDa

Gene Symbol

VCL

Uniprot

p18206

Uniprot link

Immunogen

A synthesized peptide derived from human Vinculin

Immunogen Range

Source

Rabbit

Clonality

Monoclonal

Isotype

Rabbit IgG

Specificity

Vinculin Antibody detects endogenous levels of total Vinculin

Subcellular location

Research Area

Cell adhesion

Positive control

Conjugation

Modification

Purification

Affinity-chromatography

Formulation

Concentration

Buffer

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

产品介绍

Clone

Target

波长

Storage

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

注意事项

Companion Products

Important

Comments

RRID

客户评价

References

T55164

货号 规格 价格(¥)
T55164M 100μl
T55164S 50μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13162017139(微信同号)

技术支持:15618194176(微信同号)

总机:021-34695901

南方经销商负责:手机13122837132(微信同号)          
北方及西南经销商负责:手机13122150513(微信同号)

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