This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain] CTSD CPSD

Human Mouse Rat

WB,IHC,ICC,IP,FCM

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:20

46kDa/28kDa

CTSD CPSD

p07339

https://www.uniprot.org/uniprotkb/p07339

A synthesized peptide derived from human Cathepsin D

Rabbit

Monoclonal

Rabbit IgG

Cathepsin D Antibody detects endogenous levels of total Cathepsin D

proteolysis,

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.