Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.

G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene) CCND1 BCL1 PRAD1

Human Mouse Rat

WB,IHC,ICC/IF,IP

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:100 IP 1:50

34kDa

CCND1 BCL1 PRAD1

p24385

https://www.uniprot.org/uniprotkb/p24385

A synthesized peptide derived from human Cyclin D1

Rabbit

Monoclonal

Rabbit IgG

Cyclin D1 Antibody detects endogenous levels of total Cyclin D1

Cell division #DNA damage #Lactation

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

AB_2936910