Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.

Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) HSPA8 HSC70 HSP73 HSPA10

Human Mouse Rat

WB,IHC,ICC/IF,IP,FCM

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 FC 1:30

70kDa

HSPA8 HSC70 HSP73 HSPA10

p11142

https://www.uniprot.org/uniprotkb/p11142

A synthesized peptide derived from human Hsc70

Rabbit

Monoclonal

Rabbit IgG

Hsc70 Antibody detects endogenous levels of total Hsc70

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.