IKK-beta is a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.

Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1) IKBKB IKKB

Human Mouse Rat

WB,IHC,ICC/IF

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

87kDa

IKBKB IKKB

o14920

https://www.uniprot.org/uniprotkb/o14920

A synthesized peptide derived from human IKK beta

Rabbit

Monoclonal

Rabbit IgG

IKK beta Antibody detects endogenous levels of total IKK beta

Inflammatory response #Innate immunity

Affinity-chromatography

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.