The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.

Lamin-B1 LMNB1 LMN2 LMNB

Human Mouse Rat

WB,IHC,IF/ICC,IP

WB 1:3000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

70kDa

LMNB1 LMN2 LMNB

P20700

https://www.uniprot.org/uniprotkb/p20700

Rabbit

Monoclonal

Rabbit IgG

Nucleus localization

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at -20 °C. Stable for 12 months from date of receipt.